All Phenotypes Nqo2<tm1Akj> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nqo2^tm1Akj
targeted mutation 1, Anil K Jaiswal
MGI:2447336

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nqo2^tm1Akj/Nqo2^tm1Akj	Not Specified	MGI:3522037

Allelic Composition	Nqo2^tm1Akj/Nqo2^tm1Akj
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nqo2^tm1Akj mutation (0 available); any Nqo2 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased skin tumor incidence ( J:92400 )

• in two stage tests increased sensitivity to chemically induced tumors

hematopoietic system

abnormal lymphopoiesis ( J:80549 )

• reduced numbers of circulating lymphocytes

increased granulocyte number ( J:80549 )

thrombocytosis ( J:80549 )

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:80549 )

• less susceptible to vitamin K3 toxicity (menadione)

immune system

abnormal lymphopoiesis ( J:80549 )

• reduced numbers of circulating lymphocytes

increased granulocyte number ( J:80549 )

integument

increased skin tumor incidence ( J:92400 )

• in two stage tests increased sensitivity to chemically induced tumors

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24