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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nkx3-1tm1Saa
targeted mutation 1, Sarki A Abdulkadir
MGI:2447385
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Nkx3-1tm1Saa/Nkx3-1tm1Saa
Tg(KLK3-cre)13Saa/? 		involves: C57BL/6 MGI:3046062


Genotype
MGI:3046062
cn1
Allelic
Composition		 Nkx3-1tm1Saa/Nkx3-1tm1Saa
Tg(KLK3-cre)13Saa/?
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nkx3-1tm1Saa mutation (0 available); any Nkx3-1 mutation (38 available)
Tg(KLK3-cre)13Saa mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased prostate intraepithelial neoplasia incidence ( J:74350 )
• prostatic intraepithelial neoplasia foci present
preneoplasia ( J:74350 )
• focal epithelial hyperplasia

reproductive system
increased prostate intraepithelial neoplasia incidence ( J:74350 )
• prostatic intraepithelial neoplasia foci present

endocrine/exocrine glands
increased prostate intraepithelial neoplasia incidence ( J:74350 )
• prostatic intraepithelial neoplasia foci present




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory