About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tsg101tm1.1Kuw
targeted mutation 1.1, Kay-Uwe Wagner
MGI:2447444
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tsg101tm1.1Kuw/Tsg101tm1.1Kuw Not Specified MGI:2447779
ht2
 		Tsg101tm1.1Kuw/Tsg101+ Not Specified MGI:2447780


Genotype
MGI:2447779
hm1
Allelic
Composition		 Tsg101tm1.1Kuw/Tsg101tm1.1Kuw
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsg101tm1.1Kuw mutation (0 available); any Tsg101 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:80891 )
• blastocyts were indistinguishable from wild-type littermates at E3.5, but homozygous embryos were undetectable after the implantation stage




Genotype
MGI:2447780
ht2
Allelic
Composition		 Tsg101tm1.1Kuw/Tsg101+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsg101tm1.1Kuw mutation (0 available); any Tsg101 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
neoplasm ( J:80891 )
N
• mice more than 21 months of age did not exhibit any palpable tumors




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory