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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(PSEN1)S8-4Dbo
transgene insertion S8-4, David R Borchelt
MGI:2447452
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(APP695)3Dbo/0
Tg(PSEN1)S8-4Dbo/0
involves: C57BL/6J * C3H/HeJ MGI:3663623


Genotype
MGI:3663623
cx1
Allelic
Composition
Tg(APP695)3Dbo/0
Tg(PSEN1)S8-4Dbo/0
Genetic
Background
involves: C57BL/6J * C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APP695)3Dbo mutation (3 available)
Tg(PSEN1)S8-4Dbo mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• no immunoreactive amyloid beta deposits found in cortex or hippocampus from 9 or 12 month old mice as compared to double transgenic mice: Tg(APP695)3Dbo/0, Tg(PSEN1)5Dbo/0





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory