immune system
• unlike in Smarca4tm1Grc/Smarca4tm1Grc Tg(Lck-cre)1Cwi mice, a CD4-CD8+ population is not observed
• 25% of the post-DN3 population is composed of CD4-DN4 cells compared to 9% in Smarca4tm1Grc/Smarca4tm1Grc Tg(Lck-cre)1Cwi Tg(LCKprBCL2L1)12Sjk mice
• 39% of the post-DN3 population is composed of CD4+DN4 cells compared to 52% in Smarca4tm1Grc/Smarca4tm1Grc Tg(Lck-cre)1Cwi Tg(LCKprBCL2L1)12Sjk mice
• mice exhibit two CD4+ populations with different levels of CD4 expression
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hematopoietic system
• unlike in Smarca4tm1Grc/Smarca4tm1Grc Tg(Lck-cre)1Cwi mice, a CD4-CD8+ population is not observed
• 25% of the post-DN3 population is composed of CD4-DN4 cells compared to 9% in Smarca4tm1Grc/Smarca4tm1Grc Tg(Lck-cre)1Cwi Tg(LCKprBCL2L1)12Sjk mice
• 39% of the post-DN3 population is composed of CD4+DN4 cells compared to 52% in Smarca4tm1Grc/Smarca4tm1Grc Tg(Lck-cre)1Cwi Tg(LCKprBCL2L1)12Sjk mice
• mice exhibit two CD4+ populations with different levels of CD4 expression
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endocrine/exocrine glands