Analysis Tools
digestive/alimentary system
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• 2- to 3- fold increase in the fractional absorption of dietary plant sterols
• the fractional absorption of dietary cholesterol was not significantly different
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homeostasis/metabolism
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• 2- to 3- fold increase in the fractional absorption of dietary plant sterols
• the fractional absorption of dietary cholesterol was not significantly different
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• approximately 30-fold increase in plasma sitosterol
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• the cholesterol synthesis rate was significantly lower in the adrenal gland of the female mutant mice
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• plasma cholesterol level was significantly lower than controls on a normal diet
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• on a 2% cholesterol diet, plasma cholesterol levels increased significantly more than in wild-type controls
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• liver cholesterol level was significantly lower than controls on a normal diet
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• on a 2% cholesterol diet, liver cholesterol levels increased significantly more than in wild-type controls
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liver/biliary system
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• liver cholesterol level was significantly lower than controls on a normal diet
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• on a 2% cholesterol diet, liver cholesterol levels increased significantly more than in wild-type controls
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• bilary cholesterol concentrations were extremely low
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hematopoietic system
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• at 5 to 7 months of age, show marked macrothrombocytopenia
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• at 5 to 7 months of age, show marked macrothrombocytopenia
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