Analysis Tools
mortality/aging
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• animals with impaired limb coordination die at around 2 weeks of age
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behavior/neurological
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• in some animals
• starts as a tremor when mice are a few days old
• quickly becomes worse over several days until all coordination is lost
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skeleton
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• calcified lumps develop in some mice at a few months of age
• frequency of calcifications increases with age
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• occasional appearance of calcified lumps in tendons
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• calcified lumps occasionally found attached to vertebrae
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limbs/digits/tail
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• calcified lumps occasionally found attached to the bones of the feet
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muscle
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• occasional appearance of calcified lumps in tendons
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pigmentation
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• colors of individual hairs within patches are variable
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• pigment cells within hairs have variable pigment levels, from normal to almost no pigment
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mottled coat
(
J:13104
)
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• patches of full color and patches of white on a light colored background
• patches seldom cross the midline
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integument
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• colors of individual hairs within patches are variable
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• pigment cells within hairs have variable pigment levels, from normal to almost no pigment
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mottled coat
(
J:13104
)
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• patches of full color and patches of white on a light colored background
• patches seldom cross the midline
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• sometimes of a finer texture than normal
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waved hair
(
J:13104
)
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• sometimes
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• always
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