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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Pcp2-ATXN1*30Q)2Horr
transgene insertion 2, Harry T Orr
MGI:2447853
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Pcp2-ATXN1*30Q)2Horr/Tg(Pcp2-ATXN1*30Q)2Horr involves: FVB/N MGI:5518639
tg2
Tg(Pcp2-ATXN1*30Q)2Horr/0 involves: FVB/N MGI:5518626


Genotype
MGI:5518639
tg1
Allelic
Composition
Tg(Pcp2-ATXN1*30Q)2Horr/Tg(Pcp2-ATXN1*30Q)2Horr
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• some Purkinje cell dendritic atrophy, notably some pruning of the finer dendritic branches
• reduction in molecular layer thickness
• mean relative height of climbing fiber terminals among Purkinje cell dendrites is reduced compared to wild-type mice, indicating compromised extension of climbing fiber terminals on Purkinje cells dendrites into the molecular layer




Genotype
MGI:5518626
tg2
Allelic
Composition
Tg(Pcp2-ATXN1*30Q)2Horr/0
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit a normal neurological phenotype, showing no cerebellar pathology or ataxia for more than 1 year





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory