Analysis Tools|
Allele Symbol Allele Name Allele ID |
Igf2rtm1Rlj targeted mutation 1, Randy L Jirtle MGI:2447856 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• the paternally-inherited Igf2r allele is normally silenced through genomic imprinting so embryos inheriting the floxed Igf2r allele maternally are functionally muscle-specific homozygous knockouts
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• no histologic differences are detected
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• mice show no significant differences from wild-type in body or organ weights
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• the paternally-inherited Igf2r allele is normally silenced through genomic imprinting so embryos inheriting the floxed Igf2r allele maternally are functionally liver-specific homozygous knockouts
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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