Phenotypes associated with this allele

• Allele Symbol: Ccr8^tm1Vnk
• Allele Name: targeted mutation 1, Chandrasekar Venkataraman
• Allele ID: MGI:2447885
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccr8^tm1Vnk/Ccr8^tm1Vnk	involves: 129P2/OlaHsd * C57BL/6	MGI:2654510

Genotype
MGI:2654510

hm1

• Allelic Composition: Ccr8^tm1Vnk/Ccr8^tm1Vnk
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:80898 )

• homozygotes are viable, overtly normal, and show no significant differences in the total cell numbers and percentages of different subpopulations in spleen, thymus, and lymph nodes relative to wild-type mice

• contrary to expectation, homozygotes show normal development of pulmonary eosinophilia and Th2 cytokine responses in a mouse model of allergen-induced airway inflammation using two different OVA immunization protocols