reproductive system
• XX mice develop testes with Sertoli cells but no germ cells
• caused by upregulation of SOX9
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• XX mice develop internal and external male genitalia
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vision/eye
• caused by inappropriate expression of SOX9 in the retinal pigmented epithilium
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pigmentation
• light coat color and pigmented ears co-segregate with the transgene whcih containes a tyrosinase mingene providing an easliy detectable visual marker
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integument
• light coat color and pigmented ears co-segregate with the transgene whcih containes a tyrosinase mingene providing an easliy detectable visual marker
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