All Phenotypes Fbxl3<Ovtm> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fbxl3^Ovtm
overtime
MGI:2449078

Summary

7 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxl3^Ovtm/Fbxl3^Ovtm	BTBR T⁺ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu	MGI:2661870
hm2	Fbxl3^Ovtm/Fbxl3^Ovtm	involves: BTBR * C57BL/6J	MGI:5484574
hm3	Fbxl3^Ovtm/Fbxl3^Ovtm	involves: BTBR/J * C3H/HeJ * C57BL/6J	MGI:3717257
ht4	Fbxl3^Ovtm/Fbxl3⁺	BTBR T⁺ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu	MGI:2661872
ht5	Fbxl3^{Gt(FHCRC-GT-S13-12G1)Sor}/Fbxl3^Ovtm	involves: BTBR/J * C3H/HeJ * C57BL/6J	MGI:3717258
cx6	Fbxl3^Ovtm/Fbxl3^Ovtm Nr1d1^tm1Schb/Nr1d1^tm1Schb	involves: 129S2/SvPas * BTBR	MGI:5494574
cx7	Fbxl21^Psttm/Fbxl21^Psttm Fbxl3^Ovtm/Fbxl3^Ovtm	involves: BTBR * C57BL/6J	MGI:5484573

Allelic Composition	Fbxl3^Ovtm/Fbxl3^Ovtm
Genetic Background	BTBR T⁺ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3^Ovtm mutation (1 available); any Fbxl3 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:83419 )

• homozygous mutant mice display a longer free running period than that of wild-type mice (25.88 hrs vs.23.27 hrs 0.13 sd)

Allelic Composition	Fbxl3^Ovtm/Fbxl3^Ovtm
Genetic Background	involves: BTBR * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3^Ovtm mutation (1 available); any Fbxl3 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:194037 )

• period length is 26 hr

Allelic Composition	Fbxl3^Ovtm/Fbxl3^Ovtm
Genetic Background	involves: BTBR/J * C3H/HeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3^Ovtm mutation (1 available); any Fbxl3 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:122872 )

• circadian period is extended to 26.2 hours compared to 25.8 in wild-type mice

Allelic Composition	Fbxl3^Ovtm/Fbxl3⁺
Genetic Background	BTBR T⁺ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3^Ovtm mutation (1 available); any Fbxl3 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:83419 )

• heterozygous mutant mice display a longer free running period than that of wild-type mice (23.97 hrs vs.23.27 hrs 0.13 sd)

Allelic Composition	Fbxl3^{Gt(FHCRC-GT-S13-12G1)Sor}/Fbxl3^Ovtm
Genetic Background	involves: BTBR/J * C3H/HeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3^{Gt(FHCRC-GT-S13-12G1)Sor} mutation (1 available); any Fbxl3 mutation (43 available)
Fbxl3^Ovtm mutation (1 available); any Fbxl3 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:122872 )

• circadian period is extended similar to in Fbxl3^Ovtm homozygotes

Allelic Composition	Fbxl3^Ovtm/Fbxl3^Ovtm Nr1d1^tm1Schb/Nr1d1^tm1Schb
Genetic Background	involves: 129S2/SvPas * BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3^Ovtm mutation (1 available); any Fbxl3 mutation (43 available)
Nr1d1^tm1Schb mutation (1 available); any Nr1d1 mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:194250 )

N	• 23.7 hour circadian rhythm is relatively normal

Allelic Composition	Fbxl21^Psttm/Fbxl21^Psttm Fbxl3^Ovtm/Fbxl3^Ovtm
Genetic Background	involves: BTBR * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl21^Psttm mutation (1 available); any Fbxl21 mutation (26 available)
Fbxl3^Ovtm mutation (1 available); any Fbxl3 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:194037 )

N	• circadian period is 23.16 hr similar to that in wild-type controls and significantly shorter than the predicted 24.4 hr of an additive effect

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