All Phenotypes Pck1<tm1.1Mgn> MGI Mouse

Phenotypes associated with this allele

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pck1^tm1.1Mgn/Pck1^tm1.1Mgn	involves: 129S6/SvEvTac	MGI:3029208
cn2	Pck1^tm1.1Mgn/Pck1^tm1.1Mgn Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: 129S6/SvEvTac	MGI:3029211

Allelic Composition	Pck1^tm1.1Mgn/Pck1^tm1.1Mgn
Genetic Background	involves: 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pck1^tm1.1Mgn mutation (1 available); any Pck1 mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:63929 )

• viable and fertile; normal expression of the floxed gene was noted

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased liver glycogen level ( J:63929 )

• hepatic glycogen content was decreased at birth, reduced in older mutant animals and was depleted after a 24 hour fast

increased liver triglyceride level ( J:63929 )

• hepatic triglyceride levels were increased by 94% after a 24 hour fast

liver/biliary system

enlarged liver ( J:63929 )

• after a 24 hour fast, the liver mass was increased by 71% over controls

increased liver weight ( J:63929 )

• liver weight was increased by 18%