mortality/aging
• incomplete penetrance; some mutant mice die by weaning age, although others may survive to adulthood and breed
|
craniofacial
malocclusion
(
J:78986
)
• most mutant mice get malocclusion
|
• homozygous mutants are recognizable at about 14 days of postnatal development by their odd shaped face
|
short snout
(
J:78986
)
• mice are described as having a short snout
|
growth/size/body
malocclusion
(
J:78986
)
• most mutant mice get malocclusion
|
• homozygous mutants are recognizable at about 14 days of postnatal development by their odd shaped face
|
short snout
(
J:78986
)
• mice are described as having a short snout
|
• mice are described as having an odd body shape
|
hearing/vestibular/ear
• ABR results showed that two homozygous mutant mice tested at 49 days of age exhibited intermediate hearing loss (about 25 dB above normal) and two +/? littermate control mice had normal hearing
|
limbs/digits/tail
kinked tail
(
J:78986
)
skeleton
malocclusion
(
J:78986
)
• most mutant mice get malocclusion
|