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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
snol
snubnose-like
MGI:2449570
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
snol/snol C3H/HeJ-snol/GrsrJ MGI:2449606


Genotype
MGI:2449606
hm1
Allelic
Composition
snol/snol
Genetic
Background
C3H/HeJ-snol/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
snol mutation (1 available); any snol mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Short nose, and odd face and body shape in a snol/snol mouse (right) compared to sibling control (left)

mortality/aging
• incomplete penetrance; some mutant mice die by weaning age, although others may survive to adulthood and breed

craniofacial
• most mutant mice get malocclusion
• homozygous mutants are recognizable at about 14 days of postnatal development by their odd shaped face
• mice are described as having a short snout

growth/size/body
• most mutant mice get malocclusion
• homozygous mutants are recognizable at about 14 days of postnatal development by their odd shaped face
• mice are described as having a short snout
• mice are described as having an odd body shape

hearing/vestibular/ear
• ABR results showed that two homozygous mutant mice tested at 49 days of age exhibited intermediate hearing loss (about 25 dB above normal) and two +/? littermate control mice had normal hearing

limbs/digits/tail

skeleton
• most mutant mice get malocclusion





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory