Phenotypes associated with this allele

• Allele Symbol: Tenm4^l7Rn3-5R
• Allele Name: mutation 5, Oak Ridge
• Allele ID: MGI:2449641
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tenm4^l7Rn3-5R/Tenm4^l7Rn3-5R	FRCH.Cg-Tenm4^l7Rn3-5R	MGI:3789296
hm2	Tenm4^l7Rn3-5R/Tenm4^l7Rn3-5R	involves: BALB/cRl * C3H/Rl * C57BL/10Rl	MGI:2449642

Genotype
MGI:3789296

hm1

• Allelic Composition: Tenm4^l7Rn3-5R/Tenm4^l7Rn3-5R
• Genetic Background: FRCH.Cg-Tenm4^l7Rn3-5R

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:96673 )

• mutant embryos die between E9.5 and E11.5

embryo

embryonic growth retardation ( J:96673 )

• developmental delay is noted by E5.0 and by E8.5 homozygotes lag behind by 1 day compared to controls

abnormal embryonic tissue morphology ( J:96673 )

• embryos fail to elongate and have general mesodermal defects resulting in uncoordinated somite segregation

failure of chorioallantoic fusion ( J:96673 )

• a rudimentary allantois forms, but does not fuse completely with the chorionic plate

growth/size/body

embryonic growth retardation ( J:96673 )

• developmental delay is noted by E5.0 and by E8.5 homozygotes lag behind by 1 day compared to controls

Genotype
MGI:2449642

hm2

• Allelic Composition: Tenm4^l7Rn3-5R/Tenm4^l7Rn3-5R
• Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

mortality/aging

prenatal lethality, complete penetrance ( J:54592 )