Phenotypes associated with this allele

• Allele Symbol: D17Aus9^df10J
• Allele Name: deficiency 10 Jackson
• Allele ID: MGI:2449784
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	D17Aus9^df10J/D17Aus9^df10J	involves: 129S4/SvJae * BALB/cJ * C57BL/6	MGI:3719880
cx2	D17Aus9^df10J/T^7J	involves: 129S4/SvJae * BALB/cJ * C57BL/6	MGI:3719876

Genotype
MGI:3719880

hm1

• Allelic Composition: D17Aus9^df10J/D17Aus9^df10J
• Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:81651 )

• no embryos were detected at E6.5

• however, embryos cultured from E3.5 were normal indicating embryos failed to implant or died after implantation

embryo

embryonic growth arrest ( J:81651 )

• embryonic development arrests prior to turning

cardiovascular system

distended pericardium ( J:81651 )

• at E9.5, pericardia are ballooning

Genotype
MGI:3719876

cx2

• Allelic Composition: D17Aus9^df10J/T^7J
• Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:81651 )

• embryos are absorbed by E10.5

embryo

failure of initiation of embryo turning ( J:81651 )

• mice do not undergo turning

embryonic growth arrest ( J:81651 )

• development is arrested at E9.5 with only 3 to 4 somites developed

absent notochord ( J:81651 )

• no discernible notochord is observed