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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apctm2Mmt
targeted mutation 2, Makoto M Taketo
MGI:2449941
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apctm2Mmt/Apctm2Mmt involves: 129X1/SvJ MGI:3811533
ht2
 		Apctm2Mmt/Apc+ involves: 129X1/SvJ MGI:3811534
ht3
 		Apctm2Mmt/Apctm3Mmt involves: 129X1/SvJ * C57BL/6N MGI:3811543


Genotype
MGI:3811533
hm1
Allelic
Composition		 Apctm2Mmt/Apctm2Mmt
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm2Mmt mutation (0 available); any Apc mutation (158 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3811534
ht2
Allelic
Composition		 Apctm2Mmt/Apc+
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm2Mmt mutation (0 available); any Apc mutation (158 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm

digestive/alimentary system




Genotype
MGI:3811543
ht3
Allelic
Composition		 Apctm2Mmt/Apctm3Mmt
Genetic
Background		 involves: 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm2Mmt mutation (0 available); any Apc mutation (158 available)
Apctm3Mmt mutation (0 available); any Apc mutation (158 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryonic tissue morphology ( J:81402 )
• at E7.5, the anterior embryonic region is protruding from the yolk sac; more prominent at E8.5
abnormal embryonic epiblast morphology ( J:81402 )
• at E6.5, embryonic ectoderm cells remain only in the distal region
• however, visceral endoderm develops normally




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory