All Phenotypes Trp53<tm2Brd> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Trp53^tm2Brd
targeted mutation 2, Allan Bradley
MGI:2450287

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trp53^tm2Brd/Trp53^tm2Brd	involves: 129S7/SvEvBrd * C57BL/6	MGI:3720029

Allelic Composition	Trp53^tm2Brd/Trp53^tm2Brd
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53^tm2Brd mutation (3 available); any Trp53 mutation (240 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

darkened coat color ( J:80303 )

• mice have a darker coat color than heterozygotes

neoplasm

increased tumor incidence ( J:80303 )

• tumor incidence is similar to that see in other Trp53 alleles

integument

darkened coat color ( J:80303 )

• mice have a darker coat color than heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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