Phenotypes associated with this allele

• Allele Symbol: Pdzk1^tm1Oko
• Allele Name: targeted mutation 1, Oliver Kocher
• Allele ID: MGI:2450706
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pdzk1^tm1Oko/Pdzk1^tm1Oko	either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)	MGI:2450710

Genotype
MGI:2450710

hm1

• Allelic Composition: Pdzk1^tm1Oko/Pdzk1^tm1Oko
• Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating cholesterol level ( J:81814 )

• a significantly elevated serum cholesterol level is seen in mutant mice (160.8 8.3 mg/dl vs. 89.3 16.7 mg/dl in controls)

• all other chemical profile levels in serum, including those of markers of liver and renal function, are similar to controls

• urine chemistry profiles are all similar to controls