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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gcatm1Roes
targeted mutation 1, Jurgen Roes
MGI:2450787
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gcatm1Roes/Gcatm1Roes involves: 129P2/OlaHsd * 129S2/SvPas MGI:2651666


Genotype
MGI:2651666
hm1
Allelic
Composition		 Gcatm1Roes/Gcatm1Roes
Genetic
Background		 involves: 129P2/OlaHsd * 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gcatm1Roes mutation (2 available); any Gca mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to endotoxin shock ( J:81436 )
• increased resistance to endotoxic shock
• 40% survive 100ng dose of lipopolysaccharide injected with D-galactosamine sensitizer - 100% lethal dose in controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory