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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Gabra6-cre)B1Lfr
transgene insertion B1, Louis F Reichardt
MGI:2450934
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Neurod1tm1.1Kan/Neurod1tm1.1Kan
Tg(Gabra6-cre)B1Lfr/0 		involves: 129P2/OlaHsd * C57BL/6 * DBA/2 MGI:3607799
cn2
 		Hbs1ltm1c(KOMP)Wtsi/Hbs1ltm1c(KOMP)Wtsi
Tg(Gabra6-cre)B1Lfr/0 		involves: 129S4/SvJaeSor * C57BL/6NTac * DBA/2 MGI:6718856
cn3
 		Pelotm1Slac/Pelotm1Slac
Tg(Gabra6-cre)B1Lfr/0 		involves: C57BL/6J * DBA/2 MGI:6718862
cn4
 		Mcutm1c(EUCOMM)Hmgu/Mcutm1c(EUCOMM)Hmgu
Tg(Gabra6-cre)B1Lfr/0 		involves: C57BL/6N * DBA/2 MGI:6393523


Genotype
MGI:3607799
cn1
Allelic
Composition		 Neurod1tm1.1Kan/Neurod1tm1.1Kan
Tg(Gabra6-cre)B1Lfr/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neurod1tm1.1Kan mutation (0 available); any Neurod1 mutation (29 available)
Tg(Gabra6-cre)B1Lfr mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:101098 )
N
• conditional mutants are viable and fertile with normal cerebellum size and foliation




Genotype
MGI:6718856
cn2
Allelic
Composition		 Hbs1ltm1c(KOMP)Wtsi/Hbs1ltm1c(KOMP)Wtsi
Tg(Gabra6-cre)B1Lfr/0
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6NTac * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hbs1ltm1c(KOMP)Wtsi mutation (0 available); any Hbs1l mutation (51 available)
Tg(Gabra6-cre)B1Lfr mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:306384 )
N
• mice exhibit normal cell survival of terminally differentiated granule cells even in the presence of the n-TRtct5 deficiency




Genotype
MGI:6718862
cn3
Allelic
Composition		 Pelotm1Slac/Pelotm1Slac
Tg(Gabra6-cre)B1Lfr/0
Genetic
Background		 involves: C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pelotm1Slac mutation (0 available); any Pelo mutation (15 available)
Tg(Gabra6-cre)B1Lfr mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:306384 )
N
• mice exhibit normal cell survival of terminally differentiated granule cells even in the presence of the n-TRtct5 deficiency




Genotype
MGI:6393523
cn4
Allelic
Composition		 Mcutm1c(EUCOMM)Hmgu/Mcutm1c(EUCOMM)Hmgu
Tg(Gabra6-cre)B1Lfr/0
Genetic
Background		 involves: C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcutm1c(EUCOMM)Hmgu mutation (2 available); any Mcu mutation (27 available)
Tg(Gabra6-cre)B1Lfr mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:281635 )
N
• normal calcium buffering capacity in granule cell mitochondria




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory