All Phenotypes Jchain<tm2(Myc)Tl> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Jchain^tm2(Myc)Tl
targeted mutation 2, Tomas Leanderson
MGI:2451105

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Jchain^tm2(Myc)Tl/Jchain^tm2(Myc)Tl	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6	MGI:3762623

Allelic Composition	Jchain^tm2(Myc)Tl/Jchain^tm2(Myc)Tl
Genetic Background	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jchain^tm2(Myc)Tl mutation (0 available); any Jchain mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal humoral immune response ( J:71355 )

• mutant mice were immune competent, and distinct phenotype compared to other Igj allele mutants Igj^tm1Tl and Igj^tm3Tl with increased Ig production and enhanced humoral immune response after immunization

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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