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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Jchaintm2(Myc)Tl
targeted mutation 2, Tomas Leanderson
MGI:2451105
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Jchaintm2(Myc)Tl/Jchaintm2(Myc)Tl involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 MGI:3762623


Genotype
MGI:3762623
hm1
Allelic
Composition		 Jchaintm2(Myc)Tl/Jchaintm2(Myc)Tl
Genetic
Background		 involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jchaintm2(Myc)Tl mutation (0 available); any Jchain mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal humoral immune response ( J:71355 )
• mutant mice were immune competent, and distinct phenotype compared to other Igj allele mutants Igjtm1Tl and Igjtm3Tl with increased Ig production and enhanced humoral immune response after immunization




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory