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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Egr2tm1.1Jchn
targeted mutation 1.1, James Cohen
MGI:2651550
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Egr2tm1.1Jchn/Egr2+ involves: 129S2/SvPas * C57BL/6 * DBA/2 MGI:2651556
ht2
 		Egr2tm1.1Jchn/Egr2tm1Pch involves: 129S2/SvPas * C57BL/6 * DBA/2 MGI:2651554


Genotype
MGI:2651556
ht1
Allelic
Composition		 Egr2tm1.1Jchn/Egr2+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egr2tm1.1Jchn mutation (0 available); any Egr2 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
absent rhombomere 3 ( J:82071 )
• ablation of rhombomere 3
absent rhombomere 5 ( J:82071 )
• ablation of rhombomere 5

embryo
absent rhombomere 3 ( J:82071 )
• ablation of rhombomere 3
absent rhombomere 5 ( J:82071 )
• ablation of rhombomere 5




Genotype
MGI:2651554
ht2
Allelic
Composition		 Egr2tm1.1Jchn/Egr2tm1Pch
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egr2tm1.1Jchn mutation (0 available); any Egr2 mutation (33 available)
Egr2tm1Pch mutation (1 available); any Egr2 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuronal migration ( J:82071 )
• abnormal migration of motor neuron somata out of the lateral motor column
abnormal spinal cord morphology ( J:82071 )
• ablation of boundary cap (BC) cells, putatively due to the expression of diptheria toxin
abnormal motor neuron morphology ( J:82071 )
• abnormal migration of motor neuron somata out of the lateral motor column

cellular
abnormal neuronal migration ( J:82071 )
• abnormal migration of motor neuron somata out of the lateral motor column




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory