Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ttntm1Her targeted mutation 1, Joachim Herz MGI:2651645 |
| Summary |
4 genotypes |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• resorbed embryos were observed at E15; none are found at birth
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• death at about 5 wks of age
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| N |
• the heart was reduced in size, but in proportion to reduced overall body size
• no pathology of the heart was reported
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• apparent at 3 wks of age
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• disarrayed sarcomeres, observed in less than 50% of the area of the myocytes
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• pale, widened M-lines, devoid of M-line bridges
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• resulting in abnormal posture, gait, and blepharoptosis
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| autosomal recessive limb-girdle muscular dystrophy type 2J | DOID:0110283 |
OMIM:608807 |
J:81993 | |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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