All Phenotypes Nkx6-2<tm1Ercs> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nkx6-2^tm1Ercs
targeted mutation 1, Johan Ericson
MGI:2651850

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nkx6-2^tm1Ercs/Nkx6-2^tm1Ercs	involves: 129P2/OlaHsd * C57BL/6	MGI:3761142
cx2	Nkx6-2^tm1Ercs/Nkx6-2⁺ Phox2b^{tm1(Phox2a)Mist}/Phox2b⁺	involves: 129P2/OlaHsd * 129S4/SvJae	MGI:3762503

Allelic Composition	Nkx6-2^tm1Ercs/Nkx6-2^tm1Ercs
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nkx6-2^tm1Ercs mutation (1 available); any Nkx6-2 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:71607 )

• mice homozygous for the mutant alleles were born at Mendelian frequency and survived through adulthood

Allelic Composition	Nkx6-2^tm1Ercs/Nkx6-2⁺ Phox2b^{tm1(Phox2a)Mist}/Phox2b⁺
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJae

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nkx6-2^tm1Ercs mutation (1 available); any Nkx6-2 mutation (17 available)
Phox2b^{tm1(Phox2a)Mist} mutation (1 available); any Phox2b mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal axon extension ( J:126634 )

• axonal tracts are thinner than in wild-type mice, especially for the tenth cranial nerve

abnormal vagus ganglion morphology ( J:126634 )

• axonal tracts are thinner than in wild-type mice, especially for the tenth cranial nerve

cellular

abnormal axon extension ( J:126634 )

• axonal tracts are thinner than in wild-type mice, especially for the tenth cranial nerve

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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