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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcnh2tm1Hjd
targeted mutation 1, Henry J Duff
MGI:2652959
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kcnh2tm1Hjd/Kcnh2tm1Hjd involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:2652979


Genotype
MGI:2652979
hm1
Allelic
Composition		 Kcnh2tm1Hjd/Kcnh2tm1Hjd
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnh2tm1Hjd mutation (0 available); any Kcnh2 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased heart rate ( J:82249 )
• spontaneous and abrupt bradycardias in 6 of 21 mice examined although average cycle lengths and intervals were similar to controls

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
short QT syndrome DOID:0050793 OMIM:609620
OMIM:609621
OMIM:609622
 J:82249




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory