Phenotypes associated with this allele

• Allele Symbol: Cryaa^Aey7
• Allele Name: dominant cataract 7
• Allele ID: MGI:2653028
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cryaa^Aey7/Cryaa^Aey7	C3HeB/FeJ-Cryaa^Aey7/Ieg	MGI:2653233
ht2	Cryaa^Aey7/Cryaa^+	C3HeB/FeJ-Cryaa^Aey7/Ieg	MGI:2653234

Genotype
MGI:2653233

hm1

• Allelic Composition: Cryaa^Aey7/Cryaa^Aey7
• Genetic Background: C3HeB/FeJ-Cryaa^Aey7/Ieg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:72928 )

• clefts apparent in the subcortical zone and nucleus at 7 weeks of age; this region corresponded to regions of developing opacity; more severe than heterozygotes

cataract ( J:72928 )

• described as progressive, starting as a visible opacity in the embryonic nucleus and resulting in a zonal and nuclear opacity by 2 months of age; more severe than heterozygotes

microphthalmia ( J:72928 )

• small eyes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 9 multiple types		DOID:0110266	OMIM:604219	J:72928

Genotype
MGI:2653234

ht2

• Allelic Composition: Cryaa^Aey7/Cryaa⁺
• Genetic Background: C3HeB/FeJ-Cryaa^Aey7/Ieg

vision/eye

abnormal lens morphology ( J:72928 )

• clefts apparent in the subcortical zone and nucleus at 7 weeks of age; this region corresponded to regions of developing opacity

cataract ( J:72928 )

• described as progressive, starting as a visible opacity in the embryonic nucleus and resulting in a zonal and nuclear opacity by 2 months of age

microphthalmia ( J:72928 )

• small eyes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 9 multiple types		DOID:0110266	OMIM:604219	J:72928