Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab3tm1Lrr mutation
(0 available);
any
Gab3 mutation
(8 available)
|
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normal phenotype
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• homozygotes are viable, fertile, and developmentally and behaviorally normal, with no major defects in hematopoiesis and macrophage development, or in the development, maturation, or function of mast cells, CD4+ T cells, CD8+ T cells or B cells with respect to the induction of passive systemic anaphylaxis, delayed-type hypersensitivity reaction, or response to LCMV infection
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Allelic Composition |
Gab3tm1Lrr/Y
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Genetic Background |
involves: 129S4/SvJae * C57BL/6 |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab3tm1Lrr mutation
(0 available);
any
Gab3 mutation
(8 available)
|
|
|
normal phenotype
|
• hemizygotes are viable, fertile, and developmentally and behaviorally normal, with no major defects in hematopoiesis and macrophage development, or in the development, maturation, or function of mast cells, CD4+ T cells, CD8+ T cells or B cells with respect to the induction of passive systemic anaphylaxis, delayed-type hypersensitivity reaction, or response to LCMV infection
|