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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gab3tm1Lrr
targeted mutation 1, Larry R Rohrschneider
MGI:2654214
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gab3tm1Lrr/Gab3tm1Lrr involves: 129S4/SvJae * C57BL/6 MGI:3848030
ot2
Gab3tm1Lrr/Y involves: 129S4/SvJae * C57BL/6 MGI:2654219


Genotype
MGI:3848030
hm1
Allelic
Composition
Gab3tm1Lrr/Gab3tm1Lrr
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab3tm1Lrr mutation (0 available); any Gab3 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• homozygotes are viable, fertile, and developmentally and behaviorally normal, with no major defects in hematopoiesis and macrophage development, or in the development, maturation, or function of mast cells, CD4+ T cells, CD8+ T cells or B cells with respect to the induction of passive systemic anaphylaxis, delayed-type hypersensitivity reaction, or response to LCMV infection




Genotype
MGI:2654219
ot2
Allelic
Composition
Gab3tm1Lrr/Y
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab3tm1Lrr mutation (0 available); any Gab3 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• hemizygotes are viable, fertile, and developmentally and behaviorally normal, with no major defects in hematopoiesis and macrophage development, or in the development, maturation, or function of mast cells, CD4+ T cells, CD8+ T cells or B cells with respect to the induction of passive systemic anaphylaxis, delayed-type hypersensitivity reaction, or response to LCMV infection





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory