Phenotypes associated with this allele

• Allele Symbol: dblr
• Allele Name: doubleridge
• Allele ID: MGI:2654910
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	dblr/dblr	involves: C57BL/6J * SJL/J	MGI:2654927

Genotype
MGI:2654927

hm1

• Allelic Composition: dblr/dblr
• Genetic Background: involves: C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal apoptosis ( J:82633 )

• reduced apoptosis in the interdigital regions of the forelimbs observed at E13.5

limbs/digits/tail

polydactyly ( J:82633 )

• affected animals have a 6th digit in postaxial region of both forelimbs, branching from and fused with the 5th digit

• the forelimb is abnormal in all mutant animals but abmormalities in the hindlimb are rare

syndactyly ( J:82633 )

• affected animals have a 6th digit in postaxial region of both forelimbs, branching from and fused with the 5th digit

• the forelimb is abnormal in all mutant animals but abnormalities in the hindlimb are rare

• skeletal preps reveal that only soft tissues are fused in most animals

kinked tail ( J:82633 )

• observed in one third of mutant mice

vision/eye

microphthalmia ( J:82633 )

• eye defects were observed in one third of mutant mice

anophthalmia ( J:82633 )

• eye defects were observed in one third of mutant mice