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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		H19tm1.1Sriv
targeted mutation 1.1, Madhulika Srivastava
MGI:2655221
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		H19tm1.1Sriv/H19tm1.1Sriv involves: 129S1/Sv * 129X1/SvJ * FVB/N MGI:3722120
ht2
 		H19tm1.1Sriv/H19tm1Tilg involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * FVB/N MGI:3722123


Genotype
MGI:3722120
hm1
Allelic
Composition		 H19tm1.1Sriv/H19tm1.1Sriv
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H19tm1.1Sriv mutation (0 available); any H19 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:82595 )
N
• methylation at the H19 promoter is normal




Genotype
MGI:3722123
ht2
Allelic
Composition		 H19tm1.1Sriv/H19tm1Tilg
Genetic
Background		 involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H19tm1.1Sriv mutation (0 available); any H19 mutation (12 available)
H19tm1Tilg mutation (1 available); any H19 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal DNA methylation ( J:82595 )
• methylation is altered such that maternal Igf2 is aberrantly expressed




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory