Analysis Tools|
Allele Symbol Allele Name Allele ID |
Grin1tm1.1Slab targeted mutation 1.1 Ralf Schoepfer MGI:2655232 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice died within 6 hours of birth
• no milk uptake even after the removal of wild-type pups
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice died within 1 hour of birth
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• absence of whisker-related patterning in the brainstem trigeminal complex
• however, no difference is seen between external brain morphology or weight relative to control mice
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• absence of patterned synapses of trigeminal afferents and their target cells (barrelettes)
• normal topographic mapping of primary trigeminal afferents
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• NMDA receptors are functional but lack coincidence detection properties
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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