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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ifnar1tm1Uka
targeted mutation 1, Ulrich Kalinke
MGI:2655303
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cd19tm1(cre)Cgn/Cd19+
Ifnar1tm1Uka/Ifnar1tm1Uka 		B6.129P2-Cd19tm1(cre)Cgn Ifnar1tm1Uka MGI:3829380


Genotype
MGI:3829380
cn1
Allelic
Composition		 Cd19tm1(cre)Cgn/Cd19+
Ifnar1tm1Uka/Ifnar1tm1Uka
Genetic
Background		 B6.129P2-Cd19tm1(cre)Cgn Ifnar1tm1Uka
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (11 available); any Cd19 mutation (60 available)
Ifnar1tm1Uka mutation (0 available); any Ifnar1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgG1 level ( J:129128 )
• serum IgG1 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG2a level ( J:129128 )
• serum IgG2a levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG3 level ( J:129128 )
• serum IgG3 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgM level ( J:129128 )
• serum IgM levels are markedly decreased compared to controls 10- days after immunization with soluble antigen + IFNalpha stimulation

hematopoietic system
decreased IgG1 level ( J:129128 )
• serum IgG1 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG2a level ( J:129128 )
• serum IgG2a levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG3 level ( J:129128 )
• serum IgG3 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgM level ( J:129128 )
• serum IgM levels are markedly decreased compared to controls 10- days after immunization with soluble antigen + IFNalpha stimulation




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory