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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Otop1mlh
mergulhador
MGI:2655558
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Otop1mlh/Otop1mlh BALB/c-Otop1mlh MGI:5704199
hm2
 		Otop1mlh/Otop1mlh involves: BALB/cJ MGI:2655559


Genotype
MGI:5704199
hm1
Allelic
Composition		 Otop1mlh/Otop1mlh
Genetic
Background		 BALB/c-Otop1mlh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otop1mlh mutation (0 available); any Otop1 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
head tilt ( J:227974 )
• however, mice do not exhibit abnormal circling or head tossing




Genotype
MGI:2655559
hm2
Allelic
Composition		 Otop1mlh/Otop1mlh
Genetic
Background		 involves: BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otop1mlh mutation (0 available); any Otop1 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal motor capabilities/coordination/movement ( J:82639 )
• mice shake when picked up by tail
impaired swimming ( J:82639 )
• mice are unable to swim
head tilt ( J:82639 )
• head is often held in tilted position

hearing/vestibular/ear




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory