All Phenotypes Cyp27b1<tm1.1Star> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cyp27b1^tm1.1Star
targeted mutation 1.1, Rene St-Arnaud
MGI:2656261

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cyp27b1^tm1.1Star/Cyp27b1^tm1.1Star	involves: 129S1/Sv * 129X1/SvJ	MGI:3722093

Allelic Composition	Cyp27b1^tm1.1Star/Cyp27b1^tm1.1Star
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cyp27b1^tm1.1Star mutation (0 available); any Cyp27b1 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal femur morphology ( J:82529 )

• mice exhibit a 4-fold decrease in ultimate femur load and stiffness

decreased bone mineralization ( J:82529 )

• bone mineralization is impaired

rickets ( J:82529 )

limbs/digits/tail

abnormal femur morphology ( J:82529 )

• mice exhibit a 4-fold decrease in ultimate femur load and stiffness

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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