Phenotypes associated with this allele

• Allele Symbol: Hoxb13^tm4Mrc
• Allele Name: targeted mutation 4, Mario R Capecchi
• Allele ID: MGI:2656729
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hoxb13^tm4Mrc/Hoxb13^tm4Mrc	Not Specified	MGI:2656750

Genotype
MGI:2656750

hm1

• Allelic Composition: Hoxb13^tm4Mrc/Hoxb13^tm4Mrc
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:82849 )

• phenotype is stated to be identical to that of Hoxb13^tm1Mrc homozygotes

abnormal caudal vertebrae morphology ( J:82849 )

• caudal tail vertebrae are thickened and abnormally shaped

long tail ( J:82849 )

• tail length increased by approximately 1 cm

thick tail ( J:82849 )

embryo

abnormal neural tube morphology ( J:82849 )

nervous system

abnormal neuron differentiation ( J:82849 )

abnormal neural tube morphology ( J:82849 )

abnormal innervation ( J:82849 )

abnormal nervous system tract morphology ( J:82849 )

abnormal dorsal root ganglion morphology ( J:82849 )

abnormal spinal cord morphology ( J:82849 )

• overgrowth of spinal cord

increased spinal cord size ( J:82849 )

skeleton

abnormal vertebral column morphology ( J:82849 )

abnormal caudal vertebrae morphology ( J:82849 )

• caudal tail vertebrae are thickened and abnormally shaped

behavior/neurological

hyporesponsive to tactile stimuli ( J:82849 )

cellular

abnormal neuron differentiation ( J:82849 )