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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ackr1tm1Skmz
targeted mutation 1, Kazuhisa Sekimizu
MGI:2656980
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ackr1tm1Skmz/Ackr1tm1Skmz involves: 129P2/OlaHsd * C57BL/6J MGI:2656983


Genotype
MGI:2656983
hm1
Allelic
Composition		 Ackr1tm1Skmz/Ackr1tm1Skmz
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ackr1tm1Skmz mutation (1 available); any Ackr1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal homeostasis ( J:82938 )
• rapid clearance of the chemokines eotaxin and MCP-1 from plasma
abnormal chemokine level ( J:82938 )
• plasma concentrations of eotaxin and MCP-1 are decreased compared to wild-type

immune system
abnormal chemokine level ( J:82938 )
• plasma concentrations of eotaxin and MCP-1 are decreased compared to wild-type




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory