cellular
• 3-fold
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• 2.6-fold increase in cells synthesizing DNA compared with wild-type mice
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digestive/alimentary system
• 3-fold
|
• 2.6-fold increase in cells synthesizing DNA compared with wild-type mice
|
• crypt to villus axis is increased compared to in wild-type mice
• higher increase in villi and crypt length following whole body irradiation
• shorter intestine compared with wild-type mice
• however, total surface area of intestinal epithelium is normal
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• increased differentiation
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endocrine/exocrine glands
• increased differentiation
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homeostasis/metabolism
• following whole body irradiation, mice exhibit increased number of regenerating villi and a higher increase in villi and crypt length compared with in wild-type mice
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