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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Pgr)3Shy
transgene insertion 3, G Shyamala
MGI:2657219
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(CMV-GAL4)1Shy/0
Tg(Pgr)3Shy/0 		Not Specified MGI:2657222


Genotype
MGI:2657222
cx1
Allelic
Composition		 Tg(CMV-GAL4)1Shy/0
Tg(Pgr)3Shy/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CMV-GAL4)1Shy mutation (2 available)
Tg(Pgr)3Shy mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal mammary gland development ( J:83103 )
• in about 20% of mutants, the fat pad in mammary glands is not completely filled, no lateral branching is observed, and even in the absence of fat pad filling, glands do not contain any end-buds, indicating cessation of growth
• mammary glands, on serial transplantation, undergo premature arrest in ductal growth without alterations in lobulo-alveolar growth

integument
abnormal mammary gland development ( J:83103 )
• in about 20% of mutants, the fat pad in mammary glands is not completely filled, no lateral branching is observed, and even in the absence of fat pad filling, glands do not contain any end-buds, indicating cessation of growth
• mammary glands, on serial transplantation, undergo premature arrest in ductal growth without alterations in lobulo-alveolar growth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory