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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pax2tm1Cjt
targeted mutation 1, Clifford J Tabin
MGI:2657223
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pax2tm1Cjt/Pax2tm1Cjt involves: 129S1/Sv * C57BL/6J MGI:3694691


Genotype
MGI:3694691
hm1
Allelic
Composition		 Pax2tm1Cjt/Pax2tm1Cjt
Genetic
Background		 involves: 129S1/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax2tm1Cjt mutation (0 available); any Pax2 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
absent kidney ( J:74492 )
• homozygotes lack kidneys
absent ureter ( J:74492 )
• homozygotes lack ureters and genital tracts

hearing/vestibular/ear
abnormal inner ear morphology ( J:74492 )
• homozygotes exhibit inner ear defects
absent cochlea ( J:74492 )
• homozygotes fail to develop a cochlea

nervous system
absent cochlear ganglion ( J:74492 )
• homozygotes fail to develop a spiral ganglion




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory