Phenotypes associated with this allele

• Allele Symbol: Vhl^tm1Bjg
• Allele Name: targeted mutation 1, Brian J Gavin
• Allele ID: MGI:2658719
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vhl^tm1Bjg/Vhl^tm1Bjg	Not Specified	MGI:3046852

Genotype
MGI:3046852

hm1

• Allelic Composition: Vhl^tm1Bjg/Vhl^tm1Bjg
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:48254 )

• development continues to 9.5 days after which mutant embryos undergo necrosis and resorption

embryo

abnormal pharyngeal arch morphology ( J:48254 )

• on a gross morphological level, the branchial arches appear to be severely affected

embryonic growth retardation ( J:48254 )

• homozygous mutant embryos show delays in early embryonic development

abnormal limb bud morphology ( J:48254 )

• on a gross morphological level, the limb buds appear to be severely affected

craniofacial

abnormal pharyngeal arch morphology ( J:48254 )

• on a gross morphological level, the branchial arches appear to be severely affected

limbs/digits/tail

abnormal limb bud morphology ( J:48254 )

• on a gross morphological level, the limb buds appear to be severely affected

growth/size/body

embryonic growth retardation ( J:48254 )

• homozygous mutant embryos show delays in early embryonic development