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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rtn4tm3.1Matl
targeted mutation 3.1, Marc Tessier-Lavigne
MGI:2661204
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rtn4tm3.1Matl/Rtn4tm3.1Matl involves: 129S7/SvEvBrd MGI:2661223
hm2
 		Rtn4tm3.1Matl/Rtn4tm3.1Matl involves: 129S7/SvEvBrd * C57BL/6 MGI:4353805


Genotype
MGI:2661223
hm1
Allelic
Composition		 Rtn4tm3.1Matl/Rtn4tm3.1Matl
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4tm3.1Matl mutation (0 available); any Rtn4 mutation (131 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:4353805
hm2
Allelic
Composition		 Rtn4tm3.1Matl/Rtn4tm3.1Matl
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4tm3.1Matl mutation (0 available); any Rtn4 mutation (131 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal central nervous system regeneration ( J:151085 )
• significantly fewer corticospinal tract axons are present rostrally to a spinal cord injury compared to controls
• caudally to the injury site no differences are observed




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory