Phenotypes associated with this allele

• Allele Symbol: Tal1^tm2Sho
• Allele Name: targeted mutation 2, Stuart Orkin
• Allele ID: MGI:2661471
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tal1^tm2Sho/Tal1^tm2Sho Tg(Mx1-cre)1Cgn/0	involves: C57BL/6 * CBA	MGI:2661473

Genotype
MGI:2661473

cn1

• Allelic Composition: Tal1^tm2Sho/Tal1^tm2Sho; Tg(Mx1-cre)1Cgn/0
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:83215 )

• 5% lethality, surviving mutants had an intact floxed allele

hematopoietic system

anemia ( J:83215 )

• moderate anemia at 4 and 2 weeks after the initiation of poly(I)-poly(C) (pIpC) treatment to induce cre expression

thrombocytopenia ( J:83215 )

• moderate thrombocytopenia at 2 and 4 weeks after the initiation of pIpC treatment