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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Etv1tm1Wds
targeted mutation 1, William D Snider
MGI:2663693
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Etv1tm1Wds/Etv1tm1.1Wds
Isl1tm1(cre)Tmj/Isl1+ 		involves: 129X1/SvJ MGI:3720888
cn2
 		Etv1tm1Wds/Etv1tm1Wds
Tg(PLAT-cre)116Sdu/0 		Not Specified MGI:5506524


Genotype
MGI:3720888
cn1
Allelic
Composition		 Etv1tm1Wds/Etv1tm1.1Wds
Isl1tm1(cre)Tmj/Isl1+
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv1tm1.1Wds mutation (0 available); any Etv1 mutation (44 available)
Etv1tm1Wds mutation (2 available); any Etv1 mutation (44 available)
Isl1tm1(cre)Tmj mutation (0 available); any Isl1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal proprioceptive neuron morphology ( J:83461 )
• proprioceptive afferents terminate prematurely in the intrmediate zone of the spinal cord




Genotype
MGI:5506524
cn2
Allelic
Composition		 Etv1tm1Wds/Etv1tm1Wds
Tg(PLAT-cre)116Sdu/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv1tm1Wds mutation (2 available); any Etv1 mutation (44 available)
Tg(PLAT-cre)116Sdu mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased sensory neuron number ( J:197913 )
• mutants show a 65-70% decrease in DRG neuron number at L2 levels compared to controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory