Phenotypes associated with this allele

• Allele Symbol: Fabp1^tm1Bin
• Allele Name: targeted mutation 1, Bert Binas
• Allele ID: MGI:2664854
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fabp1^tm1Bin/Fabp1^tm1Bin	involves: 129/Ola * C57BL/6	MGI:2669201

Genotype
MGI:2669201

hm1

• Allelic Composition: Fabp1^tm1Bin/Fabp1^tm1Bin
• Genetic Background: involves: 129/Ola * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal glucose homeostasis ( J:83875 )

• a small glucose level decrease seen in homozygotes

liver/biliary system

abnormal hepatobiliary system physiology ( J:83875 )

• increases in phospholipids, cholesterol and cholesterol esters, however fasting serum levels of triglycerides and fatty acids were normal

• fatty acid binding capacity of low molecular weight liver cytosolic proteins was reduced

• increased (1.4X) sterol carrier protein-2 (SCP-2)

• SCP-x reduced (4X)

• no significant decrease in total liver cytosol proteins and liver weight and histology was normal