cardiovascular system
endocrine/exocrine glands
• reduced size
|
|
• 64% reduction in weight relative to wild-type, 6 to 7 weeks of age
• no weight difference relative to wild-type between 3 and 4 weeks of age
|
|
• 50% reduction in weight relative to wild-type
|
|
• 23% reduction in weight relative to wild-type, 6 to 7 weeks of age
• no weight difference relative to wild-type between 3 and 4 weeks of age
|
growth/size/body
• reduced weight was first observed at E16.5 and first significant at E18.5, at which point there was 10% reduction relative to wild-type
• body weights, relative to wild-type, were reduced by 24% at birth and 31% at 3 weeks of age
|
enlarged lung
(
J:57958
)
• increased size
|
homeostasis/metabolism
• reduced in females
|
• reduced in females by 71% (4 weeks) and 53% (12 weeks) in the pituitary
• no reduction was observed in male mice
|
reproductive system
|
• 64% reduction in weight relative to wild-type, 6 to 7 weeks of age
• no weight difference relative to wild-type between 3 and 4 weeks of age
|
|
• 50% reduction in weight relative to wild-type
|
|
• 23% reduction in weight relative to wild-type, 6 to 7 weeks of age
• no weight difference relative to wild-type between 3 and 4 weeks of age
|
|
• 64% reduction in weight relative to wild-type
|
|
• 50% reduction in weight relative to wild-type, 6 to 7 weeks of age
• no weight difference relative to wild-type between 3 and 4 weeks of age
|
|
• observed in crosses between mutant females and wild-type males
|
infertility
(
J:57958
)
• no offspring yielded by intercrossing
|
respiratory system
enlarged lung
(
J:57958
)
• increased size
|
nervous system
• reduced size
|