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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gab1tm1Ajw
targeted mutation 1, Albert J Wong
MGI:2667211
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gab1tm1Ajw/Gab1tm1Ajw involves: 129X1/SvJ * C57BL/6 MGI:2670623


Genotype
MGI:2670623
hm1
Allelic
Composition		 Gab1tm1Ajw/Gab1tm1Ajw
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab1tm1Ajw mutation (0 available); any Gab1 mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, complete penetrance ( J:83953 )
• died in utero between day E13.5 and E18.5
• developmental defects in the heart, placenta and skin are similar to those previously reported for disruptions in this gene

cardiovascular system

embryo




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory