About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rad23atm1Jhjh
targeted mutation 1, Jan H J Hoeijmaker
MGI:2668469
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rad23atm1Jhjh/Rad23atm1Jhjh involves: 129P2/OlaHsd * C57BL/6 MGI:2672043
cx2
Rad23atm1Jhjh/Rad23atm1Jhjh
Rad23btm1Gvh/Rad23b+
involves: 129P2/OlaHsd * C57BL/6 MGI:2672047
cx3
Rad23atm1Jhjh/Rad23a+
Rad23btm1Gvh/Rad23btm1Gvh
involves: 129P2/OlaHsd * C57BL/6 MGI:2672056
cx4
Rad23atm1Jhjh/Rad23atm1Jhjh
Rad23btm1Gvh/Rad23btm1Gvh
involves: 129P2/OlaHsd * C57BL/6 MGI:2672067


Genotype
MGI:2672043
hm1
Allelic
Composition
Rad23atm1Jhjh/Rad23atm1Jhjh
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad23atm1Jhjh mutation (0 available); any Rad23a mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:2672047
cx2
Allelic
Composition
Rad23atm1Jhjh/Rad23atm1Jhjh
Rad23btm1Gvh/Rad23b+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad23atm1Jhjh mutation (0 available); any Rad23a mutation (12 available)
Rad23btm1Gvh mutation (0 available); any Rad23b mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:2672056
cx3
Allelic
Composition
Rad23atm1Jhjh/Rad23a+
Rad23btm1Gvh/Rad23btm1Gvh
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad23atm1Jhjh mutation (0 available); any Rad23a mutation (12 available)
Rad23btm1Gvh mutation (0 available); any Rad23b mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• however, cells are capable of nucleotide excision repair
• embryos survive at least through E13.5 when mouse embryo fibroblasts were isolated




Genotype
MGI:2672067
cx4
Allelic
Composition
Rad23atm1Jhjh/Rad23atm1Jhjh
Rad23btm1Gvh/Rad23btm1Gvh
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad23atm1Jhjh mutation (0 available); any Rad23a mutation (12 available)
Rad23btm1Gvh mutation (0 available); any Rad23b mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• embryos die sometime between E8.5 and E10.5

cellular
• embryos are deficient in nucleotide excision repair

homeostasis/metabolism
• embryos are deficient in nucleotide excision repair





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory