digestive/alimentary system
• increase in the number of goblet cells in the ileum, however no other morphological abnormalities in the intestine
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• enterocyte sucrase enzyme activity is decreased to less than 35% of wild-type
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• administration of T3 to induce hyperthyroidism stimulates higher proliferation of crypt cells compared to wild-type, despite similar blood concentrations of T3
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homeostasis/metabolism
• enterocyte sucrase enzyme activity is decreased to less than 35% of wild-type
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cellular
• increase in the number of goblet cells in the ileum, however no other morphological abnormalities in the intestine
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• administration of T3 to induce hyperthyroidism stimulates higher proliferation of crypt cells compared to wild-type, despite similar blood concentrations of T3
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