Phenotypes associated with this allele

• Allele Symbol: Kcnip2^tm1Krc
• Allele Name: targeted mutation 1, Kenneth R Chien
• Allele ID: MGI:2671134
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnip2^tm1Krc/Kcnip2^tm1Krc	involves: Black Swiss	MGI:2671136

Genotype
MGI:2671136

hm1

• Allelic Composition: Kcnip2^tm1Krc/Kcnip2^tm1Krc
• Genetic Background: involves: Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

irregular heartbeat ( J:76843 )

• no baseline arrhythmias but could be stimulated to induce either atrial or ventricular arrhythmias

abnormal impulse conducting system conduction ( J:76843 )

• duration of action potential increased as stimulation frequency increased

• outward potassium ion currents lack rapid activating and inactivating components

abnormal ST segment ( J:76843 )

• elevated ST segment but otherwise normal ECG pattern