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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
inft9
infertility 9
MGI:2671691
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
inft9/inft9 Not Specified MGI:3026723


Genotype
MGI:3026723
hm1
Allelic
Composition
inft9/inft9
Genetic
Background
Not Specified
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phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• normal external genitalia, seminal vesicle size, testicular descent and seminiferous tubules
• sperm with either stumped, short tails or looped tails were present
• severely reduced epididymal sperm count
• many sperm exhibited club-shaped heads
• absence of forwardly progressive motile sperm
• block of spermatogenesis at the round spermatid formation stage (J:85113)
• spermatogenic arrest at stage X, with spermatids in step 10 of spermiogenesis; apoptotic nuclei were noted in spermatids and in the tubule lumen (J:89386)

cellular
• sperm with either stumped, short tails or looped tails were present
• severely reduced epididymal sperm count
• many sperm exhibited club-shaped heads
• absence of forwardly progressive motile sperm





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory